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Pharmacological inhibitors of extracellular signal-regulated mitogen protein kinases (ERKs) attenuate the generation of apoptosis by cisplatin via glutathione-independent reduction of intracellular drug content

机译：细胞外信号调节的促分裂原蛋白激酶（ERKs）的药理抑制剂通过不依赖谷胱甘肽的减少细胞内药物含量来减轻顺铂引起的凋亡

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11 páginas, 9 figuras -- PAGS nros. 269-279

机译：11页9图-PAGS号269-279

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Amrán, Donna; Sancho, Patricia; Fernández, Carlos; Esteban, Diego; Ramos, Adrián M.; Blas, Elena de; Gómez, Milagros; Palacios, María A.; Aller, Patricio;
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年度 2005
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正文语种 eng
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1. Pharmacological inhibitors of extracellular signal-regulated protein kinases attenuate the apoptotic action of cisplatin in human myeloid leukemia cells via glutathione-independent reduction in intracellular drug accumulation [J] . Amran D, Sancho P, Fernandez C, Biochimica et biophysica acta. Molecular cell research . 2005,第3期

机译：细胞外信号调节蛋白激酶的药理抑制剂通过不依赖谷胱甘肽减少细胞内药物的积累来减弱顺铂在人骨髓白血病细胞中的凋亡作用
2. Pharmacological and Genetic Evaluation of Proposed Roles of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase (MEK), Extracellular Signal-regulated Kinase (ERK), and p90RSK in the Control of mTORC1 Protein Signaling by Phorbol Esters [J] . Bruno Fonseca, Tommy Alain, Leona Finestone, The Journal of biological chemistry . 2011,第31期

机译：促丝瘤激活蛋白激酶/细胞外信号调节激酶激酶激酶激酶激酶（MEK），细胞外信号调节激酶（ERK）和P90RSK对MTORC1蛋白信号传导的方法的药理学和遗传评价
3. E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory responses by topical administration. [J] . Muramoto K, Goto M, Inoue Y, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2010,第1期

机译：E6201，一种有丝分裂原激活的蛋白激酶/细胞外信号调节激酶激酶-1和有丝分裂原激活的蛋白激酶/细胞外信号调节激酶激酶激酶-1的新型激酶抑制剂：通过局部给药对皮肤炎症反应的体内作用。
4. Development of Novel Extracellular Signal-Regulated Kinase (ERK) Inhibitors [D] . Cornwell, Stephen. 2021

机译：新型细胞外信号调节激酶（ERK）抑制剂的发展
5. Pharmacological and Genetic Evaluation of Proposed Roles of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase (MEK) Extracellular Signal-regulated Kinase (ERK) and p90RSK in the Control of mTORC1 Protein Signaling by Phorbol Esters [O] . Bruno D. Fonseca, Tommy Alain, Leona K. Finestone, 2011

机译：药理学和遗传学评估丝裂素活化的蛋白激酶/细胞外信号调节激酶（MEK）细胞外信号调节激酶（ERK）和p90RSK在通过Phorbol Esters控制mTORC1蛋白信号中的作用
6. Pharmacological inhibitors of extracellular signal-regulated protein kinases attenuate the apoptotic action of cisplatin in human myeloid leukemia cells via glutathione-independent reduction in intracellular drug accumulation [O] . Amrán Donna, Sancho Patricia, Fernández Carlos, 2005

机译：细胞外信号调节蛋白激酶的药理抑制剂通过不依赖谷胱甘肽减少细胞内药物的积累来减弱顺铂在人骨髓白血病细胞中的凋亡作用
7. Hepatocyte Growth Factor Inhibits Apoptosis by the Profibrotic Factor Angiotensin II via Extracellular Signal-regulated Kinase 1/2 in Endothelial Cells and Tissue Explants [R] . Lee, Y. H., Marquez, A. P., Mungunsukh, O., 2010

机译：肝细胞生长因子通过细胞外信号调节激酶1/2在内皮细胞和组织外植体中抑制促纤维化因子血管紧张素II的凋亡

Pharmacological inhibitors of extracellular signal-regulated mitogen protein kinases (ERKs) attenuate the generation of apoptosis by cisplatin via glutathione-independent reduction of intracellular drug content

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